{"id":2111,"date":"2018-02-07T16:23:21","date_gmt":"2018-02-07T13:23:21","guid":{"rendered":"http:\/\/polymerjournal.kiev.ua\/en\/?page_id=2111"},"modified":"2018-02-07T16:23:39","modified_gmt":"2018-02-07T13:23:39","slug":"2014-4-14","status":"publish","type":"page","link":"http:\/\/polymerjournal.kiev.ua\/en\/2014-4-14\/","title":{"rendered":"2014 (4) 14"},"content":{"rendered":"<p><strong>Studying of bioactivity and biocompatibility of polyurethane ureas with physically immobilized folate-ferrocene conjugate<\/strong><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong><em>L.V. Makeieva, I.I. Gladyr, R.A. Roznova, D.V. Kulyesh, T.U. Zakashun, V.P. Gryzenko<\/em><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>Institute of Macromolecular Chemistry NAS of Ukraine<\/p>\n<p>48, Kharkivske shose, Kyiv, 02160, Ukraine<\/p>\n<p>&nbsp;<\/p>\n<p>Polym. J., 2014, <strong>36<\/strong>, no. 4: 434-439.<\/p>\n<p>&nbsp;<\/p>\n<p>Section: Medecine polymers.<\/p>\n<p>&nbsp;<\/p>\n<p>Language: Ukrainian.<\/p>\n<p>&nbsp;<\/p>\n<p>Abstract:<\/p>\n<p><em>New polyurethane ureas based on polyoxypropylene glycol and 2,4-;2,6-toluene diisocyanate, using diamines (1,6-hexamethylenediamine or 4,4&#8242;-diaminodiphenylmethane) as chain extenders and physically immobilized folate-ferrocene conjugate were obtained. Termophysical, mechanical, histological and biochemical investigations were carried out. It is set that prolonged form of folate-ferrocene conjugate is biocompatible during implantation in the organism of experimental animals and has biological activity.<\/em><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Key words: <\/strong>folate-ferrocene conjugate, polyurethane ureas, biological activity, biocompatibility.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u041b\u0456\u0442\u0435\u0440\u0430\u0442\u0443\u0440\u0430<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>1. \u041c\u0430\u0437\u0443\u0440 \u041b.\u041c., \u0420\u043e\u0436\u043d\u043e\u0432\u0430 \u0420.\u0410., \u0414\u0440\u043e\u0437\u0434\u043e\u0432\u0430 \u0412.\u0406., \u0413\u0430\u043b\u0430\u0442\u0435\u043d-\u043a\u043e \u041d.\u0410. \/\/ \u041f\u043e\u043b\u0456\u043c\u0435\u0440. \u0436\u0443\u0440\u043d. \u2013 2007. \u2013 29, \u2116 1. \u2013 \u0421. 58-66.<br \/>\n2. \u0416\u0435\u0440\u043d\u043e\u0432\u0430 \u041b.\u041c., \u041b\u0443\u0433\u043e\u0432\u0441\u044c\u043a\u0430 \u0413.\u0413., \u041f\u043e\u0447\u0438\u043d\u043e\u043a \u041e.\u0412., \u0413\u0430\u043b\u0430\u0442\u0435\u043d\u043a\u043e \u041d.\u0410. \/\/ \u041a\u043e\u043c\u043f\u043e\u0437\u0438\u0446. \u043f\u043e\u043b\u0456\u043c\u0435\u0440. \u043c\u0430\u0442\u0435\u0440\u0456\u0430\u043b\u0438. \u2013 2001. &#8211; 23, \u2116 2. \u2013 \u0421. 139-143.<br \/>\n3. \u0410\u043d\u0434\u0440\u044e\u0448\u0438\u043d\u0430 \u041e.\u0421., \u0420\u043e\u0436\u043d\u043e\u0432\u0430 \u0420.\u0410., \u0413\u0430\u043b\u0430\u0442\u0435\u043d\u043a\u043e \u041d.\u0410., \u041d\u0430\u0440\u043e\u0436\u0430\u0439\u043a\u043e \u041b.\u0424. \/\/ \u041d\u0430\u0443\u043a. \u0437\u0430\u043f\u0438\u0441\u043a\u0438 \u041d\u0430\u0423\u041a\u041c\u0410. \u0421\u0435\u0440\u0456\u044f: \u0425\u0456\u043c\u0456\u0447\u043d\u0456 \u043d\u0430\u0443\u043a\u0438 \u0456 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0456\u0457. \u2013 2010. \u2013 \u0422. 105. \u2013 \u0421. 47-50.<br \/>\n4. \u0410\u043d\u0434\u0440\u044e\u0448\u0438\u043d\u0430 \u041e.\u0421., \u0420\u043e\u0436\u043d\u043e\u0432\u0430 \u0420.\u0410., \u041a\u0443\u043b\u0454\u0448 \u0414.\u0412., \u0413\u0430\u043b\u0430\u0442\u0435\u043d\u043a\u043e \u041d.\u0410. \/\/ \u041f\u043e\u043b\u0456\u043c\u0435\u0440. \u0436\u0443\u0440\u043d. \u2013 2011. \u2013 33, \u2116 2. \u2013 \u0421. 186-191.<br \/>\n5. \u0414\u0435\u043c\u0447\u0435\u043d\u043a\u043e \u0418.\u0411., \u0413\u0430\u043b\u0430\u0442\u0435\u043d\u043a\u043e \u041d.\u0410., \u041c\u0430\u043a\u0435\u0435\u0432\u0430 \u041b.\u0412., \u0420\u043e\u0436\u043d\u043e\u0432\u0430 \u0420.\u0410., \u041d\u0430\u0440\u0430\u0436\u0430\u0439\u043a\u043e \u041b.\u0424., \u0413\u043b\u0430\u0434\u044b\u0440\u044c \u0418.\u0418. \/\/ \u0414\u043e\u043f. \u041d\u0410\u041d \u0423\u043a\u0440\u0430\u0457\u043d\u0438 \u2013 \u2116 3. \u2013 \u0421. 143-148.<br \/>\n6. \u041a\u043e\u043c\u0430\u0440\u043e\u0432 \u0424.\u0418., \u041a\u043e\u0440\u043e\u0432\u043a\u0438\u043d \u0411.\u0424., \u041c\u0435\u043d\u044c\u0448\u0438\u043a\u043e\u0432 \u0412.\u0412. \u0411\u0438\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0432 \u043a\u043b\u0438\u043d\u0438\u043a\u0435. \u2013 \u041b\u0435\u043d\u0438\u043d\u0433\u0440\u0430\u0434: \u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0430, 1976. \u2013 383 \u0441.<br \/>\n7. \u0413\u0430\u043b\u0430\u0442\u0435\u043d\u043a\u043e \u041d.\u0410., \u0420\u043e\u0436\u043d\u043e\u0432\u0430 \u0420.\u0410., \u0410\u043d\u0434\u0440\u044e\u0448\u0438\u043d\u0430 \u0415.\u0421., \u0414\u0435\u043c\u0447\u0435\u043d\u043a\u043e \u0418.\u0411., \u041a\u0435\u0431\u0443\u043b\u0430\u0434\u0437\u0435 \u0418.\u041c. \/\/ \u041f\u043b\u0430\u0441\u0442\u0438\u0447\u043d\u0430 \u0442\u0430 \u0440\u0435\u043a\u043e\u043d\u0441\u0442\u0440\u0443\u043a\u0442\u0438\u0432\u043d\u0430 \u0445\u0456\u0440\u0443\u0440\u0433\u0456\u044f. \u2013 2013. \u2013 \u21161. \u2013 \u0421. 45-54.<br \/>\n8. \u041c\u0430\u043a\u0435\u0454\u0432\u0430 \u041b.\u0412., \u0413\u043b\u0430\u0434\u0438\u0440 \u0406.\u0406., \u0420\u043e\u0436\u043d\u043e\u0432\u0430 \u0420.\u0410., \u0414\u0435\u043c\u0447\u0435\u043d- \u043a\u043e \u0406.\u0411. \/\/ \u0414\u043e\u043f. \u041d\u0410\u041d \u0423\u043a\u0440\u0430\u0457\u043d\u0438. \u2013 2013. \u2013 \u2116 1. \u2013 \u0421. 132-137.<br \/>\n9. \u0413\u041e\u0421\u0422 25.601-80. \u041c\u0435\u0442\u043e\u0434\u044b \u043c\u0435\u0445\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u0439 \u043a\u043e\u043c\u043f\u043e\u0437\u0438\u0446\u0438\u043e\u043d\u043d\u044b\u0445 \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u043e\u0432 \u0441 \u043f\u043e\u043b\u0438\u043c\u0435\u0440\u043d\u043e\u0439 \u043c\u0430\u0442\u0440\u0438\u0446\u0435\u0439 (\u043a\u043e\u043c\u043f\u043e\u0437\u0438\u0442\u043e\u0432). \u041c\u0435\u0442\u043e\u0434 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u044f \u043f\u043b\u043e\u0441\u043a\u0438\u0445 \u043e\u0431\u0440\u0430\u0437\u0446\u043e\u0432 \u043d\u0430 \u0440\u0430\u0441\u0442\u044f\u0436\u0435\u043d\u0438\u0435 \u043f\u0440\u0438 \u043d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u043e\u0439, \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u043e\u0439 \u0438 \u043f\u043e\u043d\u0438\u0436\u0435\u043d\u043d\u043e\u0439 \u0442\u0435\u043c\u043f\u0435\u0440\u0430\u0442\u0443\u0440\u0430\u0445 \u2013 \u0412\u0432\u0435\u0434. 1981\u201307\u201301. \u2013 \u041c. : \u0418\u0437\u0434-\u0432\u043e \u0441\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043e\u0432, 1980. \u2013 22 \u0441. : \u0438\u043b.<br \/>\n10. \u0421\u0430\u0440\u043a\u0438\u0441\u043e\u0432 \u0414.\u0421., \u041f\u0435\u0442\u0440\u043e\u0432\u0430 \u042e.\u041b. \u041c\u0438\u043a\u0440\u043e\u0441\u043a\u043e\u043f\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0442\u0435\u0445\u043d\u0438\u043a\u0430. \u2013 \u041c.: \u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0430, 1996. \u2013 542 \u0441.<br \/>\n11. \u041a\u043e\u043a\u0443\u043d\u0438\u043d \u0412.\u0410. \/\/ \u0423\u043a\u0440. \u0431\u0438\u043e\u0445\u0438\u043c. \u0436\u0443\u0440\u043d. \u2013 1975. \u2013 47, \u2116 6. \u2013 \u0421. 776-790.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Studying of bioactivity and biocompatibility of polyurethane ureas with physically immobilized folate-ferrocene conjugate \u00a0 L.V. Makeieva, I.I. Gladyr, R.A. Roznova, D.V. Kulyesh, T.U. Zakashun, V.P. Gryzenko &nbsp; Institute of Macromolecular Chemistry NAS of Ukraine 48, Kharkivske shose, Kyiv, 02160, Ukraine &nbsp; Polym. J., 2014, 36, no. 4: 434-439. &nbsp; Section: Medecine polymers. &nbsp; Language: Ukrainian. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"acf":[],"_links":{"self":[{"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/pages\/2111"}],"collection":[{"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/comments?post=2111"}],"version-history":[{"count":1,"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/pages\/2111\/revisions"}],"predecessor-version":[{"id":2112,"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/pages\/2111\/revisions\/2112"}],"wp:attachment":[{"href":"http:\/\/polymerjournal.kiev.ua\/en\/wp-json\/wp\/v2\/media?parent=2111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}