2014 (3) 10

Create biosensor systems based on molecular imprinted polymer membranes for the determination of phenols in water

T.А. Sergeyeva1, D.S. Cheljadina1, L.A. Gorbach2, О.O. Brovko2, L.M. Sergeeva2, G.V. Elska1

1Institute of Molecular Biology and Genetics NAS of Ukraine

150, Zabolotnogo str., Kyiv, 03680, Ukraine

2Institute of Macromolecular Chemistry NAS of Ukraine

48 Kharkivs’ke shose, Kyiv, 02160, Ukraine

Polym. J., 2014, 36, no. 3: 289-294.

Section: Synthesis polymers.

Language: Ukrainian.

Abstract:

An analytical system for highly selective and sensitive detection of phenol based on molecularly imprinted polymer membranes, synthesized using method of in situ polymerization in a combination with the method of computational modeling, was developed. The detection limit for phenol detection comprised 50 nM, while the linear dynamic range – 50 nM–10 mM, which corresponds to the concentrations that are necessary to be detected in natural and waste waters. Stability of the developed MIP-based sensor systems was estimated as 12 months, which significantly increases stability of analogous devices based on receptors and enzymes. Applicability of the developed sensor systems for the analysis of phenols in both model solutions and real environmental samples (natural and waste waters) was proven. The developed systems are characterized with high selectivity, sensitivity, small sized and low cost.

Кeywords: molecularly imprinted polymer membranes, аn analytical system, phenol.