2023 (1) 5
https://doi.org/10.15407/polymerj.45.01.056
SILVER-CONTAINING NANOMATERIALS: PREPARATION, MORPHOLOGY, ANTIMICROBIAL AND ANTIVIRAL ACTIVITY
V.L. Demchenko,
Institute of Macromolecular Chemistry of NAS of Ukraine, 48 Kharkivske shose, Kyiv, 02155, Ukraine,
e-mail: dvaleriyl@ukr.net
ORCID 0000-0001-9146-8984
S.V. Riabov,
Institute of Macromolecular Chemistry of NAS of Ukraine, 48 Kharkivske shose, Kyiv, 02155, Ukraine,
e-mail: sergii.riabov@gmail.com
ORCID: 0000-0003-2996-3794
S.M. Kobylinskyi,
Institute of Macromolecular Chemistry of NAS of Ukraine, 48 Kharkivske shose, Kyiv, 02155, Ukraine,
e-mail: kobylinskiy@ukr.net
ORCID: 0000-0002-4915-2502
L.A. Goncharenko,
Institute of Macromolecular Chemistry NAS of Ukraine, 48, Kharkivs’ke shose, Kyiv, 02155, Ukraine,
ORCID: 0000-0003-0274-4938
M.V. Iurzhenko,
E.O. Paton Electric Welding Institute NAS of Ukraine, 11, Kazimir Malevich str., Kyiv, 03150, Ukraine,
e-mail: 4chewip@gmail.com
ORCID: 0000-0002-5535-731X
N.P. Rybalchenko,
Zabolotny Institute of Microbiology and Virology NAS of Ukraine, 154, Akademika Zabolotny str., Kyiv, 03143, Ukraine,
e-mail: nrybalchenko@ukr.net
ORCID: 0000-0002-0505-3406
K.S. Naumenko,
Zabolotny Institute of Microbiology and Virology NAS of Ukraine, 154, Akademika Zabolotny str., Kyiv, 03143, Ukraine,
e-mail: krystyn.naumenko@gmail.com
ORCID: 0000-0003-4635-0690
S.D. Zahorodnia,
Zabolotny Institute of Microbiology and Virology NAS of Ukraine, 154, Akademika Zabolotny str., Kyiv, 03143, Ukraine,
e-mail: svetazagorodnya@ukr.net
ORCID: 0000-0002-0892-772X
Polym. J., 2023, 45, no. 1: 56-68.
Section: Structure and properties.
Language: Ukrainian.
Abstract:
Infectious diseases caused by viruses and microorganisms continue to be one of the biggest health problems worldwide, despite the rapid progress in the creation of drugs and the development of pharmaceutical technologies. The risk of complications and the spread of infections in society remains high. Scientific research and the fight against viral infections, in particular with a large group of respiratory diseases caused by viruses, such as influenza viruses, parainfluenza viruses, respiratory sensitivities, adenoviruses, rhinoviruses, coronaviruses, etc., occupy an important place in modern medicine. Due to the nature, characteristics and biological and physical properties of viruses, the issues of combating them are very acute. Microorganisms resistant to many antimicrobial agents are also developing (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, etc.). Therefore, today there is an urgent need for new materials with a higher antiviral and bactericidal effect, less toxicity for humans and the environment (ecology, medicine and food industry). Silver-containing biomaterials in various forms (powders, films, solutions, products formed by 3D printing technology) with effective antimicrobial and antiviral effects have been developed. The materials are made on the basis of polyelectrolyte complexes of polysaccharides (pectin – chitosan, pectin – cationic starch, carboxymethylcellulose – cationic β-cyclodextrin, anionic starch – cationic starch) and polylactide biopolymer. Silver nanoparticles in the composition of composites were formed in environmentally friendly ways: by reduction silver ions with extracts of natural substances (green tea, mint, propolis, pectin), by methods of thermochemical reduction or cathodic sputtering of silver nanoparticles from silver foil onto the surface of the film. The structure, morphology, obtained materials and their antimicrobial, antiviral and cytotoxic properties were studied. The relationship between the structure and morphology and the protective properties of the obtained materials was studied.
Key words: biomaterials, silver nanoparticles, structure, morphology, antimicrobial and antiviral properties.
REFERENCES
1. Demchenko V., Rybalchenko N., Zahorodnia S., Naumenko К., Riabov S., Kobylinskyi S., Vashchuk A., Mamunya Ye., Iurzhenko M., Demchenko O., Adamus G., Kowalczuk M. Preparation, Characterization, Antimicrobial and Antiviral Properties of Silver-containing Nanocomposites based on Polylactic Acid–Chitosan. ACS Applied Bio Materials, 2022, 5: 2576 – 2585. https://doi.org/10.1021/acsabm.2c00034.
2. Demchenko V., Riabov S., Sinelnikov S., Radchenko O., Kobylinskyi S., Rybalchenko N. Novel approach to synthesis of silver nanoparticles in interpolyelectrolyte complexes based on pectin, chitosan, starch and their derivatives. Carbohydrate Polymers, 2020, 242: 1–13. https://doi.org/10.1016/j.carbpol.2020.116431.
3. Abbas M., Buntinx M., Deferme W., Peeters R. (Bio)polymer/ZnO Nanocomposites for Packaging Applications: A Review of Gas Barrier and Mechanical Properties. Nanomaterials, 2019, 9: 1494. https://doi.org/10.3390/nano9101494.
4. Urayama H., Kanamori T., Kimura Y. Properties and biodegradability of polymer blends of poly (L-lactide) with different optical purity of the lactate units. Macromolecular Materials and Engineering, 2002, 287: 116–121. https://doi.org/10.1002/1439-2054(20020201)287:2<116::AID-MAME116>3.0.CO;2-Z.
5. Shameli K., Ahmad M.B., Yunus W.M.Z.W., Ibrahim N.A., Rahman R.A., Jokar M., Darroudi M. Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity. International Journal Nanomedicine, 2010, 5: 573–579. https://doi.org/10.2147/IJN.S12007.
6. Nootsuwan N., Sukthavorn K., Wattanathana W., Jongrungruangchok S., Veranitisagul C., Koonsaeng N., Laobuthee A. Development of Antimicrobial Hybrid Materials from Polylactic Acid and Nano-silver Coated Chitosan. Oriental Journal of Chemistry, 2018, 34: 683–692. http://dx.doi.org/10.13005/ojc/340210.
7. Demchenko V., Kobylinskyi S., Iurzhenko M., Riabov S., Vashchuk A., Rybalchenko N., Zahorodnia S., Naumenko K., Demchenko O., Adamus G., Kowalczuk M. Nanocomposites based on polylactide and silver nanoparticles and their antimicrobial and antiviral applications. Reactive and Functional Polymers, 2022, 170: 105096. https://doi.org/10.1016/j.reactfunctpolym.2021.105096.
8. Zezin A.A. Synthesis of metal-polymer complexes and functional nanostructures in films and coatings of interpolyelectrolyte complexes. Polymer Science, 2019, A61: 754–764. https://doi.org/10.1134/S0965545X19060154.
9. Zezin A.A. Synthesis of hybrid materials in polyelectrolyte matrixes: control over sizes and spatial organization of metallic nanostructures. Polymer Science, 2016, C 58: 118–130. https://doi.org/10.1134/S1811238216010136.
10. Roto R., Rasydta H.P., Suratman A., Aprilita N.H. Effect of reducing agents on physical and chemical properties of silver nanoparticles. Indonesian Journal of Chemistry, 2018, 18: 614–620. https://doi.org/10.22146/ijc.26907.
11. Demchenko V.L., Kobylinskyi S.M., Riabov S.V., Shtompel V.I., Iurzhenko M.V., Rybalchenko N.P. Novel approach to formation of silver-containing nanocomposites by thermochemical reduction of Ag+ ions in interpolyelectrolyte-metal complexes. Applied Nanoscience, 2020, 10: 5409–5419. https://doi.org/10.1007/s13204-020-01368-0.
12. Zezin A.A., Klimov D.I., Zezina E.A., Mkrtchyan K.V., Feldman V.I. Controlled radiation-chemical synthesis of metal polymer nanocomposites in the films of interpolyelectrolyte complexes: Principles, prospects and implications. Radiation Physics and Chemistry, 2020, 169: 108076. https://doi.org/10.1016/j.radphyschem.2018.11.030.
13. Alnairat N., Dalo M.A., Abu-Zurayk R., Mallouh S.A., Odeh F., Bawab A.Al. Green Synthesis of Silver Nanoparticles as an Effective Antibiofouling Material for Polyvinylidene Fluoride (PVDF) Ultrafiltration Membrane. Polymers, 2021, 13: 3683. https://doi.org/10.3390/polym13213683.
14. Lokanathan A.R., Uddin K.M.A., Rojas O.J., Laine J. Cellulose Nanocrystal-Mediated Synthesis of Silver Nanoparticles: Role of Sulfate Groups in Nucleation Phenomena. Biomacromolecules, 2014, 15: 373–379. https://doi.org/10.1021/bm401613h.
15. Sobczak-Kupiec A., Malina D., Wzorek Z., Zimowska M. Influence of silver nitrate concentration on the properties of silver nanoparticles. Micro & Nano Letters, 2011, 6: 656–660. https://doi.org/10.1049/mnl.2011.0152.
16. Kaewvilai A., Wattanathana W., Jongrungruangchok S., Veranitisagul S., Koonsaeng N., Laobuthee A. 3,4-Dihydro-1,3-2H-benzoxazines: Novel reducing agents through one electron donation mechanism and their application as the formation of nano-metallic silver coating. Materials Chemistry and Physics, 2015, 167: 9–13. https://doi.org/10.1016/j.matchemphys.2015.10.011.
17. Behravan M., Panahi A.H., Naghizadeh A., Ziaee M., Mahdavi R., Mirzapour A. Facile green synthesis of silver nanoparticles using Berberis vulgaris leaf and root aqueous extract and its antibacterial activity. International Journal of Biological Macromolecules, 2019, 124: 148–154. https://doi.org/10.1016/j.ijbiomac.2018.11.101.
18. Yousaf H., Mehmood A., Ahmad K.S., Raffi M. Green synthesis of silver nanoparticles and their applications as an alternative antibacterial and antioxidant agents. Materials Science and Engineering: C, 2020, 112: 110901. https://doi.org/10.1016/j.msec.2020.110901.
19. Flieger J., Franus W., Panek R., Szymańska-Chargot M., Flieger W., Flieger M., Kołodziej P. Green Synthesis of Silver Nanoparticles Using Natural Extractswith Proven Antioxidant Activity. Molecules, 2021, 26: 4986. https://doi.org/10.3390/molecules26164986.
20. Abd-Elhady H.M., Ashor M.A., Hazem A., Saleh F.M., Selim S., Nahhas N. El, Abdel-Hafez S.H., Sayed S., Hassan E.A. Biosynthesis and Characterization of Extracellular Silver Nanoparticles from Streptomyces aizuneusis: Antimicrobial, Anti Larval, and Anticancer Activities. Molecules, 2022, 27: 212. https://doi.org/10.3390/molecules27010212.
21. Rizwana H., Alwhibi M.S., Al-Judaie R.A., Aldehaish H.A., Alsaggabi N.S. Sunlight-Mediated Green Synthesis of Silver Nanoparticles Using the Berries of Ribes rubrum (Red Currants): Characterisation and Evaluation of Their Antifungal and Antibacterial Activities. Molecules, 2022, 27: 2186. https://doi.org/10.3390/molecules27072186.