2016 (3) 9

https://doi.org/10.15407/polymerj.38.03.255

Novel biologically active polyurethane materials containing silver and copper nanoparticles

Yuri Savelyev, Alexey Gonchar, Boris Movchan, Alexey Gornostay, Sergey Vozianov, Adel Rudenko, Rita Rozhnova, Tamara Travinskaya

Institute of Macromolecular Chemistry NAS of Ukraine

48, Kharkivske shose, Kyiv, 02160, Ukraine; travinskaya-tamara@rambler.ru

Paton Institute of ElectroWelding NAS of Ukraine

11, Bozhenko str., Kyiv, 03680, Ukraine

Institute of Urology of NAMS of Ukraine

9А, Kotsubinskogo str., Kyiv, 04053, Ukraine

Polym. J., 2016, 38, no. 3: 255-260.

Section: Synthesis polymers.

Language: English.

Abstract:

Silver and copper nanoparticles containing biologically active thermoplastic polyurethanes have been prepared by saturation of liquid polyether (original reactant for polyurethane synthesis) with Ag, Cu nanoparticles, followed by polyurethane synthesis. The problem encountered during the synthesis of such materials is uniform incorporation and distribution of the metal nanoparticles in the polymer matrix and at the same time retention the physico-chemical properties inherent to polyurethanes. Colloid of metal nanoparticles in a liquid polyoxytetramethylene glycol, MM 1000 was obtained by electron beam evaporation technology and vacuum deposition. Then, the metal-containing thermoplastic polyurethane materials with targeted properties and structure, depending on diisocyanates and chain extenders nature, have been produced on the basis of obtained colloid. Polyurethanes containing Cu and Ag nanometals exhibit bactericidal/bacteriostatic properties against bacteria, fungi and yeast-like fungi. Standard methods of polyurethane processing allow to produce the resulting biologically active metal-containing polyurethane materials for medical products (catheters, drains, films, and so on), scince the presence of metal nanoparticles does not affect the physical properties of the polymer.

Key words: biologically active polyurethane, copper and silver nanoparticles, bactericidal/bacteriostatic properties.

References

1. 1. A.C. Balazs, T. Emrick and T.P. Russel. Nanoparticle polymer composites: where two small worlds meet. Science, 2006, 314: 1107.
2. 2. Jain P., Pradeep T. Potential of silver nanoparticle-coated polyurethane foam as an antibacterial water filter. Biotechnology and bioengineering. 2005, 90: 59–63.
3. 3. Maribel G. Guzmаn, Jean Dille, Stephan Godet. Synthesis of silver nanoparticles by chemical reduction method and their antibacterial activity. International Journal of Chemical and Biological Engineering. 2009: 104-111.
4. 4. Lamabam Sophiya Devi and S. R. Joshi. Antimicrobial and Synergistic Effects of Silver Nanoparticles Synthesized Using Soil Fungi of High Altitudes of Eastern Himalaya. Mycobiology. 2012, 40: 27–34.
5. 5. Savelyev Yu.V., Gonchar О.N, Movchan B.О., Gornostay О.V., Rudenko А.V. Method of preparation of polyurethane material. Ukrainian Patent 94092, October 27, 2014.
6. 6. Song C., Lin Y, Hu Z. Preparation of silver nanoparticles stabilized on the surface of polystyrene microspheres. Nanotecnology. 2004, 15: 962–965.
7. 7. Chou K-S., Huang K-C., Lee H-H. Inkjet printing of nanosized silver colloids. Nanotecnology. 2005, 16: 779–784.
8. 8. Shekhar Agnihotri, Soumyo Mukherji and Suparna Mukherji. Size-controlled silver nanoparticles synthesized over the range 5–100 nm using the same protocol and their antibacterial efficacy. The Royal Society of Chemistry, 2014, 4: 3974-3983.
9. 9. Oates, T., Mucklich A. Evolution of plasmon resonances during plasma deposition of silver nanoparticles // Nanotecnology. 2005, 16: 2606–2611.
10. 10. Zhenhua Tang, Ying Xiong, Minghua Tang. Temperature dependence of magnetoelectric effect in Bi3.15Nd0.85Ti3O12–La0.7Ca0.3MnO3multiferroic composite films buffered by a LaNiO3 layer. J. Mater. Chem. C., 2014, 2: 1427-1435.
11. 11. Gornostay O.V., Kovinsky I.S. Nanodimensional discrete coatings of copper oxide on crystals of sodium choride deposited from vapor phase in vacuum. Electrometallurgy Today. 2012. 107, no. 2: 50-53.
12. 12. Khavezov I., Tsalev D. Atomic-absorption analysis. L.: Chemistry, 1983: 144.
13. 13. Danilovich Yu.V., Chunikhin О.Yu., Danilovich G.V. Testing of changes of the uterus myocytes’ sizes depended on modulators action of it contractile activity by photon correlation spectroscopy. Physiology Journal. 2013. 59, no. 1: 32-40.
14. 14. Barbara J. Frisken Revisiting the method of cumulants for the analysis of dynamic light-scattering data 20 August 2001, 40, no. 24 y APPLIED OPTICS: 4087-4091.
15. 15. Standart 9.048…9.053-75 (91). Materials and products. Test methods for microbiological stability.
16. 16. Savelyev Yu.V., Goncharр О.N., Movchan B.О., Gornostay О.V., Vozianov С.О., Rudenko А.V. Method of preparation of polyurethane material. Ukrainian Patent 98460, April 27, 2015.