2016 (3) 10

https://doi.org/10.15407/polymerj.38.03.261

Biosensor system for detection of bisphenol A in aqueous solutions

T.A. Sergeyeva, A.V. Satyr, O.V. Piletska, L.A. Gorbach, О.О. Brovko, A.V. El’skaya

Institute of Molecular Biology and Genetics NAS of Ukraine

150 Zabolotnogo str., Kyiv, 03680, Ukraine

University of Leicester

Leicester LE1 7RH, United Kingdom

Institute of Macromolecular Chemistry NAS of Ukraine

48, Kharkivske shose, Kyiv, 02160, Ukraine

Polym. J., 2016, 38, no. 3: 261-266.

Section: Synthesis polymers.

Language: Ukrainian.

Abstract:

Molecularly imprinted polymer membranes based on acrylate-polyurethane semi-IPNs capable of highly-selective recognition of bisphenol A were synthesized. Composition of the MIP membranes was optimized using the method of computational modelling (molecular dynamics). The synthesized membranes were used as a basis of simple and inexpensive colorimetric sensor system for detection of bisphenol A in aqueous solutions. Selective recognition of bisphenol A by the MIP membranes is provided due to formation of selective receptor sites in their structure, which are complementary to the analyte molecules. Molecules of bisphenol A, which were adsorbed by the surface of the MIP membranes, were revealed using colored reaction with 4-aminoantipyrine. Intensity of the membranes’ staining was proportional by bisphenol A concentration in the analyzed sample. Detection limit for bisphenol A detection with the developed colorimetric sensor system comprised 50 µM, while the detection range was 50 µM – 1 mM. The developed sensor systems were tested for environmental monitoring (analysis of natural waters).

Key words: molecularly imprinted polymers, membranes, sensors, biosensors, sensor systems, bisphenol A.

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