2015 (3) 12

https://doi.org/10.15407/polymerj.37.03.299

Synthesis of surface-active cholesterylcontaining copolymers based on poly(maleic anhydride-co-ethyltrioxyethylene methacrylate)

Z.I. Demchuk1, О.G. Budishevska1, А.S. Voronov2, V.B. Vostres1, I.T. Tarnavchyk1,2, М.Z. Savka1, О.Yu. Zholobko1, S.A. Voronov1

1Lviv Polytechnic National University

12, S.Bandery STR, Lviv, 79013, Ukraine

2North Dakota State University

Dept. 2760, P.O. Box 6050, Fargo, ND 58108-6050, USA

Polym. J., 2015, 37, no. 3: 299-305.

Section: Synthesis polymers.

Language: Ukrainian.

Abstract:

Amphiphilic surfactants poly(cholesterylmaleinat-co-maleic acid-co-ethylltrioxyethylene methacrylate) (MAc-CholMAc-PEMA) with different contents of cholesteryl were synthesized by the reaction of cholesterol with a poly(maleic anhydride-co-ethyltrioxyethylene methacrylate) copolymer and followed by alkaline hydrolysis of poly(cholesterylmaleinat-co-maleic acid-co-ethylltrioxyethylene methacrylate)(CholMAc-MA-PEMA). The structures of obtained copolymers were studied with an IR and a 1H-NMR spectroscopy, a pH-metric titration. Aqueous colloids of procured copolymers are able to solubilize lipophilic substances.

Keywords: cholesterylcontaining copolymers, poly(maleic anhydride-co-ethyltrioxyethylene methacrylate), solubilization of lipophilic substances.

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